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10.1038/s41392-023-01606-1 86 SunJ.SongX.WangC.RuanQ

Vitamin B 12 is essential for the nerve and brain health, red blood cell and DNA production, metabolism and preventing anaemia

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Key findings: Deprescribing interventions significantly reduced the use of potentially inappropriate medications (PIMs) and other targeted medications

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Notably, based on the results from part 1 of the ESSENCE trial, on 15 August 2025, the FDA approved semaglutide 2.4 mg for the treatment of adults with MASH with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis)