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An upper intake level of 2 g/day was set to avoid diarrhea and gastrointestinal disturbances with high supplemental intakes

PMID: 10993921

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13 Distinguishing the skeletal effects of insulin from those of IGF-1 in vivo is complicated by the fact that most cell types express both IR and IGF-1R, as well as IR/IGFIR hybrid receptors, which can be cross-activated by the others receptors ligand

Regulation of the Erk2-Elk1 signaling pathway and megakaryocytic differentiation of Bcr-Abl(+) K562 leukemic cells by Gab2