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Tissues were immediately harvested and snap frozen in liquid N 2
According to the company, the treatment has received Breakthrough Therapy Designation by the FDA for a number of indications including post-bariatric hypoglycemia (PBH) and congenital hyperinsulinism (HI)
Briefly, isolated human T cells were stained with monoclonal antibodies to anti-CD45 (BioLegend, clone HI30, Cat
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They govern physiological processes, modulate the immune system, and can circumvent immune responses owing to their low immunogenicity and cytotoxicity