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DOI: 10.1097/SPV.0000000000001008 Keywords Darifenacin Trade Name: Enablex (extended release) Drug Class: M3 selective muscarinic antagonist Mechanism of Action: Inhibits the effects of acetylcholine mediated by M3 muscarinic receptors expressed on smooth muscle of the urinary bladder, which relaxes the bladder, and produces a antispasmodic effect

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Time-restricted eating or fasting May reduce chronically high IGF-1 and improve metabolic markers

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