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In HCC, morin enhances the efficacy of cisplatin by suppressing PARP1-mediated protective autophagy and DNA repair, while concurrently mitigating the drugs nephrotoxic side effects
Quinone compounds are notorious redox cyclers, present in drugs such as doxorubicin, which is used to treat a host of human cancers
In summary, whether in hoof DD or other skin infections, the underlying process involves disruption of skin/hoof microbial homeostasis under external stress, leading to loss of protective microbial function and dominance of pathogenic microorganisms
b - d , 3-month-old Mx1-Cre and Mx1-T3 mice were treated with -glucan or PBS and Lineage-negative cells were harvested 7 days later, differentiated into myeloid cells, treated with -glucan or PBS, further differentiated before LPS induction for 24 hr for cytokine production