Although DPP-4 inhibitors do not cross the BBB under normal conditions (the pharmacokinetic feature may prevent their repurposing use in neurodegenerative diseases), the permeability of BBB is increased in neurodegenerative diseases, so molecules otherwise unable to cross BBB could enter into CNS in these conditions (103)
If you have two vials at different concentrations and you want to draw from both to reach a specific dose, you would need to calculate the partial dose from each vial and then add the unit measurements together
Lauren Jamieson notes they can help manage dryness, sensitivity, and pigmentation caused by hormonal shifts
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review
I used a few of these in January
Also, make sure you carry it in a temperature controlled carry case so that your medication stays cool