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doi: 10.1186/s13059-021-02308-z 103 PeitzschCGorodetskaIKlusaDShiQAlvesTCPantelKet al

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six excluded those with a history of abdominal surgery or anatomical abnormalities 12 , 13 , 18 , 19 , 21 , 24 and four excluded patients using opioids, laxatives, or prokinetic agents