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Most of the compounds synthesized using substrate-based inhibitors approach, these compounds are proline mimetic, which occupy S 1 -pocket, P 2 -substituent of drug occupies S 2 -pocket whereas P 1 -substituent occupies S 1 -pocket of DPP-4 protease, and their basic structure interacts via either forming a covalent or non-covalent bond [36]

Worryingly, the rising popularity of drugs such as Ozempic (Semaglutide), has also raised important questions regarding their broader societal and socioeconomic implications

HC Guayaba: Toms Gmez Gascn, Concepcin Vargas-Machuca Cabaero, M Isabel Gutirrez Snchez, M Angeles Fernndez Abad, Margarita Beltejar Rodrguez, Javier Martnez Suberviola, Miguel Angel Real Prez, Carmen Coello Alarcn, Carlos San Andrs Pascua, Jos Antonio Granados Garrido

[DOI] [PubMed] [Google Scholar] 133.Gong Y, Han XD

Vitamin D: Supports immune health, [6] plus bone and muscle health repair

This research was supported by the project No