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For instance, liraglutide improved ED by regulating smooth muscle dysfunction and oxidative stress in a GLP-1 receptor-dependent fashion in a rat model of type 1 diabetes 99

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The peptide appears to enhance stress adaptation capacity by modulating corticotropin-releasing hormone (CRH) and ACTH secretion patterns, potentially reducing the physiological toll of chronic stress on organ systems

doi: 10.1111/j.1365-2982.2009.01422.x