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4) Long-Lasting Action Unlike natural GLP-1, which is degraded within minutes by the enzyme DPP-4, semaglutide is structurally modified to resist enzymatic breakdown

Safety and tolerability: Semaglutide has been shown to be generally safe and well-tolerated, with the most common adverse events being nausea, vomiting, and diarrhea

Here's what the science shows: In a clinical trial of adults with type 2 diabetes already taking metformin , people who added liraglutide 1.21.8 mg lost around 6 pounds after six months, compared with 3 pounds on placebo, on average

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For patients on semaglutide, whether for diabetes management or weight loss, these principles remain applicable with some practical modifications