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Because formal, large-scale Phase 3 clinical trials for Long COVID are still scaling up, researchers have relied heavily on massive patient-reported outcome surveys to see what is working in real-world clinical settings

CrossRef Mitochondrial Stress and Mitokines: Therapeutic Perspectives for the Treatment of Metabolic Diseases Benyuan Zhang, Joon Young Chang, Min Hee Lee, Sang-Hyeon Ju, Hyon-Seung Yi, Minho Shong Diabetes & Metabolism Journal.2024

While dietary tryptophan is primarily absorbed intestinally for protein synthesis, colonic microbiota extensively catabolize residual tryptophan through multiple pathways