It works by helping the body release insulin when blood sugar is high, slowing stomach emptying to reduce blood sugar spikes after meals, and decreasing liver sugar production
By reducing hunger and increasing feelings of fullness, Semaglutide helps patients lose significant amounts of weight when combined with lifestyle changes
It was first approved by the FDA in 2017 to treat Type 2 diabetes
Semaglutide is approved for obesity in nondiabetic patients
Latest Ozempic Cost Without Insurance According to Drugs.com, updated on May 8, 2026, the standard Ozempic injection cost without insurance is listed as $349 per month for 0.25 mg, 0.5 mg, or 1 mg doses, and $499 per month for the 2 mg dose through the listed participating options
When used alongside a reduced-calorie diet and increased physical activity, Wegovy has been shown to help patients lose up to 1921% of their body weight over 72 weeks (7.2mg dose) or around 1517% over 68 weeks at the standard 2.4mg dose [1]