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This mechanism effectively halts tumor growth and facilitates immune-mediated destruction of cancer cells

Regulatory status: FDA-approved as Ozempic (type 2 diabetes), Wegovy (chronic weight management), and Rybelsus (oral, type 2 diabetes)

Mohamad NorMHAyobNMokhtarNMRaja AliRATanGCWongZet al

Clinical trials demonstrate average weight loss of 15-22% with tirzepatide compared to 10-15% with semaglutide, though individual responses vary considerably

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An unknown fraction of these lesions are treated by consensus before excision (cryotherapy, fluorouracil use, etc.) resulting in distorted morphological features such as hyper or hypo pigmentation and scarring of the lesion and therefore were omitted from this study due to the lack of criteria of excision (Drno et al