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Growth/differentiation factor-15 (GDF-15) is a stress-induced cytokine expressed in multiple cell types, including cardiomyocytes, adipocytes, and macrophages

A bunch of studies from 2012 "confirms the ability of copper peptides to improve aging skin conditions, which make them indispensable in anti-aging and protective cosmetic products." Several research theories suggest that "bioactive peptides hold great potential for cancer therapy and diagnostics." Thereby indicating that peptides are safe for topical use

Davis JL, OConnor M, Erlbacher H, Schlichte SL, Stevens HE

Patients may become disappointed when they do not see a dramatic reduction in total body weight

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