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FDA approves Lilly's Foundayo (orforglipron) GLP-1 pill for weight loss owenhaskins Apr 1 2 min read The FDA has approved Eli Lilly and Companys Foundayo (orforglipron) for adults with obesity or overweight with weight-related medical problems

Last reviewed: May 12, 2026 Last updated: May 12, 2026 Written by: Jay Hastings , CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

10.1016/j.cmet.2021.01.015 [DOI] [PMC free article] [PubMed] [Google Scholar] 15.Sattar N, McGuire DK, Pavo I, Weerakkody GJ, Nishiyama H, Wiese RJ, et al

There have already been reports of organizations reversing previous coverage of GLP-1 for obesity due to high utilization and extremely high costs to the plan

Diabetes Metab Syndr Clin Res Rev 11:225230 Higashijima Y, Tanaka T, Yamaguchi J, Tanaka S, Nangaku M (2015) Anti-inflammatory role of DPP-4 inhibitors in a nondiabetic model of glomerular injury

For consumers unwilling or unable to pay for GLP-1 medications like Ozempic, Wegovy and Zepbound, the offers from compounding pharmacies rather than mainstream manufacturers of the drugs are appealing