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Compared with single Tamoxifen, or Fulvestrant, or Erastin treatment, the combination of the two drugs further inhibited the growth of ER+ breast cancer cells (Fig

This intramolecular salt bridge is present on the same face of the peptide -helix in the active state AMYR structures and rotamers of both residues constrain each other with their sidechains located close to ECL2 of the CTR protomer (Fig

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