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FGF2, fibroblast growth factor 2

In colorectal cancer cells with mutant kras, slc25a22-mediated glutaminolysis reduces DNA demethylation to increase wnt signaling, stemness, and drug resistance

A more comprehensive approach would be to concurrently measure actual protein levels (e.g., WB, ELISA, etc.) of potential targets in addition to inhibitor assays

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doi: 10.1016/j.bionps.2019.100006 181

In kidney diseases, gentamicin can induce nephrotoxicity, leading to impaired renal function, while Riceberry bran extract (RBBE) can initiate protective mechanisms in the kidneys via regulation of the PKC/NRF2 antioxidant defense pathway [49]