Many patients starting GLP-1 medications like semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound) wonder about this symptom
Some women experience insomnia initially , but this typically resolves within the first few weeks
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Start your intake How GLP-1 Fatigue Develops: Metabolic and Gastrointestinal Mechanisms GLP-1 fatigue typically arises from two mechanisms: rapid caloric restriction (appetite suppression can exceed intake by 5001000 kcal daily) and delayed gastric emptying, which reduces nutrient absorption efficiency in the short term
Improved Sleep : Poor sleep, especially from sleep apnea, can throw off hormone production
What this analysis does not include: Medical advice, treatment recommendations, or product endorsements