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Previous studies have shown hypoperfusion and reduction in the biosynthesis of neurotransmitters such as gamma aminobutyric acid (GABA), glutamate, and aspartate in the frontal, occipital, cingulate, and temporal cortices and basal ganglia

Ichikawa, R., Kimura, K., Nakamura, S., Ohkura, S

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As hypoxia-reoxygenation damage occurs in HTx due to cell occlusion, thrombin inhibition may hinder coagulation activation and inflammatory reaction triggered by hypoxia-reoxygenation damage in HTx