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Further, domain specific mutation effects of GNE were observed on mitochondrial dependent cell apoptosis 16

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The authors of the review believe these factors, taken together, might account for the consistent demonstration that the glutathione levels in the substantia nigra (a part of the brain with a role in reward and movement) were 40-50 percent lower in Parkinsons disease patients

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Well, it is a disease, and just like suboxone for narcotics addiction shuts off the drive, this is similar

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