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If you suspect your semaglutide has been exposed to temperatures above 86F (30C) or if the medication has been frozen, it should be considered potentially compromised

Notably, semaglutide is not recommended for patients with severe gastroparesis or severe gastrointestinal disease

Those with stable, quiescent disease may be reasonable candidates, provided they understand the importance of monitoring for symptom changes and maintaining close communication with both their gastroenterologist and prescribing physician

Functional for general questions but not a 24/7 option

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Both medications may cause nausea, which could be exacerbated when used together