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The balance of H 2 O 2 /O/OH is crucial for engineered stem cells to maintain genomic stability and induce DNA damage responses [304]
But rapamycin has uncertain efficacy and potential adverse effects (Moghadamnia et al., 2024)
Although evidence of efficacy is lacking, the manufacturers claim improvement of melasma, hyperpigmentation and skin ageing
This supports a direct interaction, although their underlying mechanisms are still in the early stages of investigation and further studies with larger sample sizes or validation are required (Wang Q
For example, the over-expression of A
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