It should be administered cautiously for infants and children
These changes lead to central sensitization, where non-painful stimuli are perceived as painful (allodynia), and pain responses are amplified (hyperalgesia)
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*Correspondence: Hassan Rajabi-Maham, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Coordinates have been deposited to the PDB with accession codes 9EXG, 9EX5, 9EXF, 9EXT and 9EYT
234,235 These findings need to be confirmed in larger trials