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This discovery further enriches the theoretical framework underlying lipid peroxidation in ferroptosis

The specific mechanism by which enzymatic reactions cause lipid peroxidation is that Acyl-CoA synthetase long-chain family member 4 (ACSL4) and Lysophosphatidylcholine acyltransferase-3 (LPCAT3) first activate polyunsaturated fatty acids (PUFAs) to bind to lipids in the cell membrane (e.g., phosphatidylethanolamine PE), forming the PUFA-PE complex (Su et al., 2019)

doi: 10.1080/15412550902766934 102 KirienkoD

3809-C QUALITY OF LIFE, SYMPTOM BURDEN, PSYCHOLOGICAL DISTRESS, AND PROGNOSTIC PERCEPTIONS AMONG PATIENTS WITH DECOMPENSATED CIRRHOSIS Nneka Ufere 1 , Lucinda Li 1 , John Donlan 2 , Teresa Indriolo 1 , Joyce Zhou 1 , Alyson Kaplan 3 , Alan Noll 4 , Nancy Mason 1 , Michaela Rowland 1 , Kirsten Engel 1 , Jennifer C

LKB1/STK11 Expression in Lung Adenocarcinoma and Associations with Patterns of Recurrence

Verrillo, E