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As a consequence, SELECT has raised the evidence threshold that innovators must clear when targeting conditions such as hypertension, dyslipidaemia or heart failure, including the effect size they need to demonstrate to be clinically meaningful and patient relevant

Reduced breakdown of encephalins results in increased levels of endorphins in the brain

A new beta cell-specific mitophagy reporter mouse shows that metabolic stress leads to accumulation of dysfunctional mitochondria despite increased mitophagy

Think of selectivity as being really good at one specific job

This is a behaviorally meaningful, high-bar outcome for payers, clinicians, and patients Retatrutide didnt just move weight scales

doi: 10.4274/Jcrpe.1181 111 HouJW