This could mean that even more benefit will accrue over the long-term. At this point, no one can say for sure why semaglutide prevents secondary cardiovascular eventsscientists are still studying whether there are other factors in addition to weight reduction
As with any blood donation, taking proper precautions is important staying well-hydrated, avoiding strenuous activity right after donating, and closely following any other instructions provided by the collection staff
How Does Semaglutide Work
In the definitive SURMOUNT-5 head-to-head trial (NEJM 2025), tirzepatide produced ~20% weight loss vs
The trial tracked 17,604 adults ages 45 and older who had overweight or obesity and a cardiovascular condition, but no history of diabetes
American Gastroenterological Association