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Over a 24-week period, responders exhibited significant improvements in disease activity score (DAS)28, swollen joint counts, body weight, and HbA1C, whereas non-responders showed no notable changes

Recently, IL-12/IL-23 inhibitors have been introduced as a new class of drugs for PsA management, with evidence suggesting that their efficacy is less influenced by body weight

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The pattern across the timeline is that tolerability improves as effect accrues the roughest GI window is early, precisely when weight change is smallest, and by the time therapeutic doses are driving measurable change the gut has usually adapted to each step

I do everything in my power to stay injury-free, so form always comes first

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