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In 2025, the court allowed the core failure-to-warn claims to proceed but imposed strict evidentiary requirements, requiring objective diagnostic testing to confirm gastric injury
Obesity is a major public health challenge in the UK
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Other medicines warranting caution include: Oral contraceptives the tirzepatide SmPC (Mounjaro, MHRA/emc) notes a reduction in oral contraceptive exposure during initiation and dose escalation, and advises considering additional contraceptive precautions during this period
Patients should not stop or change these medications without consulting their healthcare provider
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