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Partly because there are no decent human studies re effects of peptides

According to recommendations from nutrition institutes and the World Health Organization (WHO), the daily Recommended Dietary Allowance (RDA) is as follows: Infants 06 months: 0.4 mcg Infants 712 months: 0.5 mcg Children 13 years: 0.9 mcg Children 48 years: 1.2 mcg Children 913 years: 1.8 mcg Teenagers 14+ years and adults: 2.4 mcg Pregnant women: 2.6 mcg Breastfeeding women: 2.8 mcg Receiving adequate daily Vitamin B12 helps reduce the risk of anemia, fatigue, and neurological problems, while supporting optimal metabolic and overall bodily function

Free Rad Biol Med 2012;52(10):2128-2141

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Because it has a 2-3 on the comedogenic scale, it is a moderate risk for acne-prone skin

Mothers taking pharmacologic doses of corticosteroids should be advised not to nurse