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In the Northern Hemisphere, the late gestation coincides with the winter season, when pasture is insufficient

Metabolic rate: GH elevation increases resting metabolic rate through multiple mechanisms, including increased fatty acid oxidation, enhanced thermogenesis, and improved mitochondrial function

The combination can be particularly challenging

(PubMed) Slatore CG, Littman AJ, Au DH, Satia JA, White E

This mechanism can: Delay or reduce absorption of oral drugs Increase variability in drug exposure Be amplified by nausea, vomiting, and diarrhoea Which means Not all oral medications behave as expected Contraception: a real-world safety signal This is where the issue becomes tangible