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For instance, the influence of trans-resveratrol on fear memory impairment and anxiety-like behaviors evaluated in a time-dependent sensitization (TDS) procedure-induced post-traumatic stress disorder (PTSD) model of mice

In addition, coptisine treatment ameliorated the colitic symptoms and inhibited the inflamed lesions in mice administered with DSS [125]

Both genetic ablation and chemical inhibition of TRF1 telomeric localisation can block the growth of p53-null K-Ras G12V -induced lung carcinomas and PDGFA/B-induced glioblastomas in a telomere-length independent manner, remarkably without affecting mouse survival or tissue function 1,2,3

PLoS One 9 , e102311 (2014)

When a compound changes gene expression, it alters which proteins a cell produces potentially shifting the cell's behaviour toward repair, growth, or protection

Treatment with dopamine antagonists tends to alleviate these positive symptoms