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Immediate medical attention is required if an allergic reaction happens

This led to its popularity for metabolism and body composition, with users reporting sustained weight loss and energy gains

[1] Don't purchase over-the-counter B12 supplements without medical guidance, as this can interfere with accurate assessment and may mask underlying conditions

Nitrous oxide exposure (during surgery or recreational use) can inactivate B12 and cause rapid neurological deterioration in vulnerable individuals

This means B12 deficiency is real and underdiagnosed, but it is not universal and not everyone experiencing fatigue has a B12 problem