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ALCAR and KET increased rCMRglc at similar degrees in prefrontal, somatosensory, and cingulate cortices, and KET increased rCMRglc at a different, much larger, degree in limbic and dopaminergic areas

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Association of Coffee Consumption with Hearing and Tinnitus Based on a National Population-Based Survey

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In a few specialised situations a diabetes specialist may consider adding them to insulin in carefully selected people, but this is off-label and needs close monitoring