Impurity Formation in GLP-1 peptide drugs Liraglutide: Liraglutide, a 31-amino acid peptide, is prone to degradation and impurity formation due to its structural features
Another drug included is Saxenda, also manufactured by Novo Nordisk, which contains the active ingredient liraglutide and is approved as a weight-loss treatment
Common reasons to switch: cost, insurance coverage changes, intolerable tirzepatide side effects, medication availability, or personal preference
Demand for the drug has skyrocketed in recent years due to its effectiveness for weight loss, although its not yet FDA-approved for that purpose
Semaglutide Semaglutide is a synthetic GLP-1 RA that belongs to a class of antidiabetic agents called incretin mimetics
This threshold matters because many people assume room temperature storage means any indoor environment