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10.2337/dc17-2381 42 LiuL.ShiH.XieM.SunY.NahataM

Experimental studies have demonstrated that chronic hyperglycemia may reduce -cell expression of GLP-1 receptors, leading to diminished responsiveness to endogenous GLP-1 [7, 10]

Figure 1: Changes in A) sociability index, B) social novelty index, C) # USVs evoked, D) % marbles buried, E) grooming time in seconds between control mice and mice treated with MT-II Finally, the study explored differences in oxytocin receptor expression in the brains of MIA mice compared to normal C57BL/6J mice

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