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Eli Lilly is also not far behind and is expected to submit its FDA application by the end of this year/early next year

2) GLP-1RAPDB2022GLP-1RA60.52018-2022CAGR70.5%(~16%)(~55%) GLP-1RA GLP-1RA202251%15%;202274.4(31%)GLP-1R/GIPR20225FDA2022/2023Q14.8/5.72030GLP-1RA2350-400GLP-18GLP-1RA2%2NDA7III9II(2023.3) FDA6(Saxenda)201412GLP-1RA;Ozempic(2017,)Rybelsus(2019,)Wegovy(2021);Tirzepatide(Mounjaro)GIPR/GLP-1R20225IIGLP-1(2023.7) GLP-1(2023.7)1(2023.7)(2023.7)GLP-1R/GIPRGLP-1R/GCGRGLP-1R/GIPRGLP-1R/GCGRGLP-1R/GCGRIBI362IIIGLP-1R/GIPR/GCGRRetatrutideIIIGLP-1R/AMYRCagriSemaIII2)GLP-1RAOrforglipronDanuglipronLotiglipronOrforglipron(II)III3)GLP-1RAFcPEG/GLP-1efpeglenatideIII4)GLP-12 GLP-1 FDAGLP-1RACDMO 1 GLP-1RA 1.1 GLP-1RA 1.1.1 GLP-1 (GLP-1)L1964 60-70% T2DM 20% GLP-1()GLP-1GLP-1 1.1.2 GLP-1 GLP-1()()50mg/dLGLP-1T2DM(ISR) GLP-1 2 1.1.3 GLP-1 GLP-1 GLP-1 934021.8mg13%22% 232972(MACE) 1.1.4 GLP-1 RA GLP-1 GLP-13 (DPP-4)(DPP-4)1-2minGLP-1DPP-4GLP-1 RAGLP-1RA23N()DPP-4GLP-1()Fc()PEG()PLGA() 1.2 GLP-1RA200 1.2.1 GLP-1RA 2005GLP-1RA GLP-1Exendin-4GLP-153%2009GLP-1GLP-197%GLP-1RAGLP-1RAGLP-1RA 1)GLP-1RA 2)GLP-1RA 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HbA1c 0.5%~1.0% 1030HbA1c7%40%0.9% 30 (10 )+22.6kg (TZD) 40%-50%Excendin-438%( 85% GLP-1RANAFLD/NASHIII F2-3NASHIII202112007251)NASH(72)2)NASH(72)3)(0-240)2029 GCGRGIPRFGF21R 20236(EASL)GLP-1GCGRefinopegdutide(MK-6024)NAFLD)IIaefinopegdutideGLP-1145efinopegdutide(10mg)(1mg)24efinopegdutide72.7%(95% CI66.878.7)42.3%(95% CI36.548.1)24efinopegdutide8.5%7.1%(p=0.085)IIb2025.12.5 4.5.2 (AD): III (AD) ADAD()AD(MCI)ADAD-(A)(NFTs) GLP-1RA TauGLP-1RA1)GLP-1ADAD2)GLP-1GLP-1RAT2DM15%19%GLP-13)GLP-1 GLP-1RAAD ADGLP-1RAAb/Tau III104CDR-SB2025 5 5.1 GLP-1 5.1.1 (1982)leuprolidegoserelin(19851989)20902000-20101990-20102 5.1.2 2-99() FDA Frost & Sullivan202062820259602019-20258.8%CDMO2020202025442019-202517.7% 5.1.3 FDA6% 1940FDA6%83%11%FDA 2023H1Top108 5.1.4 1) 2) 5.1.4 BocFmoc 1)DICDCCEDCHClHOBtHOAt2)TBTUHBTUHATUPyBOP 5.1.4 + 1000kgMounjaroAPI 42.5mg/0.5mL5mg/0.5mL415mg(Mounjaro2.5mg7.5mg10mg12.5mg15mg)5mg/0.5mLDrugs.com(5mg/)~1087 1000kg5000543.5 IIISURPASS-3521000kg400 5.1.5 GLP1-RA GLP-1RACDMO 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This isnt an oral versus injectable debate, Wilson explains

Freezing damages the peptide structure and renders the medication unsafe and ineffective

Off-label use is when doctors prescribe a drug for a purpose other than what its approved to treat or help prevent