This last mile truly makes all the difference
Individual needs vary by body weight, protein goals, activity level, and food tolerance
For now, the best path forward is to stick with therapies backed by solid, long-term data, using GLP-1 agonists as a potential supplement for managing metabolic issues
Most of the subjects included in the available RCTs are PCOS patients with severe obesity, which do not reflect the entire clinical spectrum of PCOS encountered in clinical practice
Additionally, weight loss has notable benefits for reducing pain and inflammation, which is crucial for individuals dealing with chronic pain conditions
Furthermore, isolated MSCs undergo an age-dependent functional decline in stemness and undergo intrinsic alterations during in vitro culture, which also reduces their functions [9, 10]