Wilding JPH, Batterham RL, Calanna S, Davies M, Van Gaal LF, Lingvay I, McGowan BM, Rosenstock J, Tran MTD, Wadden TA, et al
The secretion of incretin hormones from enteroendocrine cells in the gut epithelium, including glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), potentiates postprandial insulin secretion, a phenomenon known as the incretin effect
Saira Naseer
Shore [52] suggests that strategies (probiotics/prebiotics) that alter the gut microbiome or/and its metabolic products, such as dietary manipulations, may represent a new frontier for treating asthma in obese individuals
J.PhamT.et al (2017)
Rare cases of severe liver injury have been reported in people taking orlistat, but it's not certain that the drug caused those problems