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Patients and methods There were twenty (12 (60%) male) consecutive patients with a median age of 71 (6376) years presenting with shortness of breath on exertion, enrolled into the prospective analysis for metabolomic profiling in the Internal Medicine and Hypertensiology Department in 2024

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The antigens are associated to MHC II molecule that interacts with T-cell receptor of T CD4 + lymphocytes, leading the antigen recognition and, subsequently, activation

10.1038/s41522-019-0097-2 78 LaskarA.EilertsenJ.LiW.YuanX