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Tirzepatide works uniquely by targeting two essential hormones produced naturally in the body: glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)

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Compared with db/db mice, the Low and High groups treated with berberine had lower blood glucose levels after intraperitoneal injection of glucose and insulin (Figures 1E, G)

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