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How do GLP-1 medications like Ozempic work

Glucagon decreases food intake and appetite by central mechanism and by reducing gastric emptying ( vice versa ( Guzman and colleagues ( Treatment of NAFLD: applicability of GLP-1RAs Potential modes of action of GLP-1RAs in NAFLD Current NAFLD treatment consists of interventions promoting bodyweight loss

Start with 1 teaspoon daily mixed in at least 812 oz of water

However, in activated PSCs, liraglutide, a GLP-1R agonist, did not stimulate release of inflammatory cytokines/chemokines, however, it stimulated PSC proliferation, which was dependent on ERK activation

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