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Tirzepatide has a dual agonist effect Tirzepatide is a newer medication that was approved by the FDA in 2021

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More severe and/or acute cases have been associated with hallucination, syncope, seizure, coma, respiratory arrest, and death

Lancet (2001) 357(9253):3547

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It's a rare eye condition, but its the second-leading cause of optic nerve blindness and can lead to permanent vision loss, according to Brigham and Womens Hospital