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Previous studies have shown a certain association between S100A9 and the occurrence and development of cardiovascular diseases, which has become a focus of our attention as well ( FIGURE 7 3.6 Semaglutide mitigates MIRI through the PKC-S100A9 pathway In order to further investigate the signaling pathways involved in the biological activity of semaglutide, we will co-culture semaglutide with cardiomyocytes under H/R conditions

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doi: 10.1081/FRI-120003416 137 AllwoodJGWakelingLTBeanDC

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Cannav SP, Riso G, Casciaro M, Di Salvo E, Gangemi S