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After 14 days of estrogen therapy, endometrial thickness was measured using a 2-dimensional vaginal ultrasound (Voluson E8, GE Healthcare, Chicago, USA)

These agents act through multiple mechanisms, including direct cardioprotection, vasodilation, natriuresis, weight reduction, lipid profile improvement, anti-inflammatory effects, renal protection, reduction in plaque formation, and neurohormonal regulation

Long term data provides clarity on these risks

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Many individuals experience improvements in cholesterol and triglyceride levels, contributing to overall cardiovascular health