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A 2025 systematic review in the HSS Journal identified 36 studies from 1993 to 2024, with consistent findings across multiple animal models and injury types

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A randomized split-face trial found that light-based vascular treatment significantly reduced facial redness and visible vessels in rosacea (a randomized split-face study of light-based treatment for rosacea redness and vessels), other studies confirm IPL is effective for rosacea-related redness (a clinical study of intense pulsed light for rosacea-associated redness), and longer follow-up shows the improvement can last (a clinical study reporting lasting rosacea clearance with intense pulsed light)

Riboflavin-5-Phosphate (Active Vitamin B2) Supports mitochondrial energy production, antioxidant pathways, and nervous system function