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It is designed as a once-weekly injectable treatment for obesity, working via amylin receptors rather than the GLP-1 pathway used by most current weight loss medications

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Ebrahimi R, Sepand MR, Seyednejad SA, Omidi A, Akbariani M, Gholami M, Sabzevari O (2019) Ellagic acid reduces methotrexate-induced apoptosis and mitochondrial dysfunction via up-regulating Nrf2 expression and inhibiting the IB/NFB in rats

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The Croatian Phase I and II trials reported no serious adverse events

Because protein binding has rapid equilibration, the total amount of drug metabolised will be independent of protein binding but highly dependent on liver blood flow