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These gastrointestinal effects are most likely to occur when you first start Saxenda or after each dose increase, and they often improve as your body adjusts over the first few weeks of treatment

Hesitation causes more pain because slow needle entry stimulates more nerve endings

A mechanistic role for leptin in human dendritic cell migration: differences between ileum and colon in health and Crohns disease

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Foods that may trigger symptoms include: Eating smaller portions and balanced meals can help reduce nausea and support more stable appetite control

Patients taking insulin or sulfonylureas should be monitored for hypoglycemia, and dose reductions of these medications may be necessary