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Compared with metformin and second- or third-line glucose-lowering medication groups, major adverse CVEs were significantly lower in patients with NAFLD and type 2 diabetes taking GLP-1RAs, but not different from those taking SGLT2 inhibitors
This preoperative optimization is particularly important for patients with nonalcoholic fatty liver disease, a condition commonly associated with obesity and insulin resistance
4b) with similar potency but lower efficacy (~10%) than glucagon (ESM Table 4)
Once-Weekly Semaglutide for Weight Management: A Clinical Review
Semaglutide is safe for most people and can be used in people with heart, liver, kidney and other many other conditions
Adding a peptide on top of an evidence based foundation should be reserved for situations where the foundation has been adequately pursued and specific residual concerns remain
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