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APE1 co-precipitates more with nucleophosmin (NPM1) in C9orf72 patient tissue lysates compared to controls (Farg et al., 2017), and overexpression of NPM1 inhibits apoptosis in neuronal cells expressing poly GR 100 and poly PR 100 (Farg et al., 2017)

PMID: 39161060

In contrast, standard BPC-157 may degrade when taken orally

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How Do People Typically Use BPC-157

If you (or your older relative) has difficulty taking medications regularly, scheduled vitamin B12 shots are often the better option