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doi: 10.3389/fimmu.2025.1675279 Received 29 July 2025 Accepted 28 October 2025 Published 20 November 2025 Volume 16 - 2025 Edited by Ali Raza Jahejo, Guangxi University, China Reviewed by Khalid Mehmood, Islamia University of Bahawalpur, Pakistan Ahmed Burghal, University of Basrah, Iraq Updates Copyright 2025 Cai and Wang